2020-07-Offer for a Thesis Allowance - Subject: Development of conductive materials for emerging contaminants detection based on an electrochemical biosensor

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Offer for a Thesis AllowanceSubject: Development of conductive materials for emerging contaminants detection based on an electrochemical biosensor

Thesis abstract

This PhD position is part of the project CAPTAIN Ad Hoc (CAPTeur pour l’Analyse IN situ des Polluants Emergents), a four-year project founded by the E2S (Energy Environment Solutions) Initiative devoted to the development of an analytical strategy to detect, in situ and in real time, emerging pollutants in aquatic environments.

Functionalization of a screen-printed electrode by a recognition biomolecule (aptamer or peptide) will allow to obtain a biosensor specific to the target molecule, recognition beingcarried out according to a key/lock scheme.

In order to enhance the sensitivity and selectivity of our electrochemical biosensors, a variety of materials can be developed and employed to modify the electrodes. Polymers, nanoparticles, self-assembling peptides and their composite materials will be developed and tested in their electronic capabilities. The most conductive oneswill be employed tomodify the electrodes and functionalize with the recognition biomolecules for the final assembling of our electrochemical platform.

 

Keywords: biosensor, contaminants, conductive materials, polymers,peptides,electrodes, recognition biomolecules, chemical functionalization, electrochemical detection

 

Working conditions

Hosting laboratory: The Institute of Analytical Sciences and Physico-Chemistry for Environment and Materials (IPREM) is a Joint Research Unit CNRS / UPPA (UMR 5254).

Laboratory expertise: The Institute of Analytical Sciences and Physical Chemistry for the Environment and Materials (IPREM) is a mixed research unit of the National Research Center for Science (CNRS) and of the UPPA (UMR 5254). Research activities focus on the development of fundamental knowledge in physical chemistry, analytical chemistry and microbiology, in relation to applications concerning the structure of living matter, environmental monitoring and the functional properties of different classes of materials. Analytical strategies, modelling, physicochemical approaches, fine studies of structures and reactivity, development, characterization and implementation at different length scales are the major skills available in the institute, which enable an original positioning in several fields of application and in various industrial sectors at both national and international levels.

Localisation: Université de Pau et des Pays de l’Adour ; Technopole Helioparc, 2 av. Président P. Angot, 64000, Pau, France

Starting date: October 2020

Length: 3 years

Employer: UPPA, doctoral school ED 211 Doctoral School of Exact Sciences and their Applications

Gross monthly salary: 1878 €, including 32h of teaching activities, each year (UPPA doctoral contract, according to E2S UPPA project)

 

Required skills and competences - Who can apply ?

The ideal candidate has a master degree in organic/polymer chemistry.
His/her work will go from the synthesis of conductive materials to the fabrication of the biosensor, comprising also the physicaland analytical characterizations.

He/she is passionate for identifying solutions to environment related concerns and for multidisciplinary research.

The candidate is rigorous and highly motivated. He/She candidate must have a good level in English and the capacity to work autonomously.

 

 

Application - Evaluation criteria

Selection process step:

  • Establishment of the selection comittee
  • Evaluation of the applicants files
  • Interview with the selected candidates and ranking

Application files will be evaluated based on the following criteria:

  • Candidate's motivation, scientific maturity and curiosity
  • Candidate's basic knowledge and experimental skills
  • Academic results : grades and ranking in M1 and M2 ; steadiness in the academic background
  • English language proficiency
  • Oral and written communication skills
  • Candidate’s ability to present her/his work and results
  • Professional experience (e.g. Work experience similar to an internship in a laboratory – or likewise, any previously achieved research work, reports, publications ...)


Application file composition

Application must be written in English and sent to the following email addresses:
luisa.ronga@univ-pau.fr (philippe.carbonniere @ univ-pau.fr)and christine.lartigau-dagron @ univ-pau.fr
with the title “Doctoral application”, and the following documents attached (altogether, in a single pdf file):

  • CV (max 2 pages) including the publication list when applicable
  • Cover letter detailing the candidate's motivations (max 2 pages)
  • Copy of your Bachelor and Master diploma (or equivalent) 
  • Copy of your Bachelor and Master transcripts (marks and ranking)
  • Any letter of recommendation
  • Contact details ( Name and e-mail addresses) of 2 referees (including the Master thesis supervisor)

 

Submission deadline : Until the position is filled