2018-11-Postdoctoral position: Large-scale analysis for metallophores in bacterial exudates using high resolution high accuracy mass spectrometry

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E2S: Energy and Environment Solutions

What is E2S UPPA?

What is E2S UPPA?


The consortium at the heart of the Energy Environment Solutions (E2S) project is a composed of the University of Pau and the Pays de l’Adour (UPPA) and two national research organisations, National Institute...

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Postdoctoral position - MESMIC projectLarge-scale analysis for metallophores in bacterial exudates using high resolution high accuracy mass spectrometry

Duties /Project description

The post-doctoral fellow will be in charge of the method development and coordination of the acquisition and collation of mass spectrometry data for metal complexes with metallophores in bacterial exudates (strains, consortia, microcosms). He (she) will interact within an interdisciplinary consortium of a dozen of permanent researchers, other post-docs and Ph.D. students in the fields of microbiology, ecology, and molecular and cellular biology. One of his(her) tasks will be feedback and advice on the conception of the experiments to maximize the quality of the data obtained and validation of the experiments of the Ph.D. students aimed at obtaining MS data. He (she) will interact with the engineers in charge of the running and maintenance of the MS platform including 3 LC- MS Orbitrap and several LC-ICP MS systems. 

Keywords: metallomics, Fourier Transform mass spectrometry, analytical chemistry, microbiology.

 

Working conditions

Laboratory: IPREM Pau and Anglet, France
IPREM is a joint Research Unit CNRS/UPPA (UMR 5254) in France. IPREM has an extensive and highly competitive research program that comprises the development of fundamental knowledge in physico-chemistry, analytical chemistry and microbiology, in relation to applications concerning the structure of the living, the management of the environment and the functional properties of different classes of materials.

Localisation: Université de Pau et des Pays de l’Adour, campus of Anglet, Pyrénées-Atlantiques, France

Starting date: February 15th, 2019.

Duration: initial appointment of 1 year extendable up to 3 years

Type of position: Full-time temporary position

Gross salary range: 35 k€ / year (which includes extra gratification for teaching duties – 64h)

Funding: This post doc position is funded by the project E2S-UPPA (Energy Environment Solutions) which has a core scientific domain that focuses on Environment and Energy to meet challenges related to the energy transition, geo-resources, aquatic habitats and the environmental effects of natural and  anthropogenic changes.
https://e2s-uppa.eu/en/index.html

 

Applicant's profile

Requirements :

  • Seniority in the French public sector of less than 2 years.
  • PhD in relevant domain
  • Sound background in mass spectrometry and liquid chromatography method development is required. Elements of biostatistics and bioinformatics are a plus.
  • Fluent knowledge of English and scientific articles writing skills.
  • Good organization and communication skills


Application procedure

Applications must be sent as a single pdf file and submitted by email to ryszard.lobinski @ univ-pau.fr and simon.godin @ univ-pau.fr

  • CV
  • A motivation letter describing the applicant’s previous research experience and how it is related to the present position (one, or maximum two pages) is also required. 
  • A short summary of your past research (2 pages maximum)
  • Contact details of three referees

 

Application deadline

Please submit your application to ryszard.lobinski @ univ-pau.fr and simon.godin @ univ-pau.fr by December 15th, 2018 , with “Post-doctoral application MESMIC” in the subject of your email.

 

 

References

Flis, P., et al. (2016). Inventory of metal complexes circulating in plant fluids: a reliable method based on HPLC coupled with dual elemental and high-resolution molecular mass spectrometric detection. New Phytologist, 211(3), 1129-1141.

Ghssein, G., et al. (2016). Biosynthesis of a broad-spectrum nicotianamine-like metallophore in Staphylococcus aureus. Science, 352(6289), 1105-1109.

Walker, L. R., et al. (2017). Unambiguous identification and discovery of bacterial siderophores by direct injection 21 Tesla Fourier transform ion cyclotron resonance mass spectrometry. Metallomics, 9(1), 82-92.

Boiteau, R. M., et al.  (2016). Siderophore-based microbial adaptations to iron scarcity across the eastern Pacific Ocean. PNAS, 113(50), 14237-14242.

Deicke, M., et al. (2014). Metallophore mapping in complex matrices by metal isotope coded profiling of organic ligands. Analyst, 139(23), 6096-6099.